Transplantation

The more compatible the donor-recipient match, the less likely for organ or stem cell rejection.

We offer a world-class leader in transplant diagnostics providing a broad portfolio of molecular and antibody-based assays to evaluate HLA compatibility between donors and recipients.

HLA Genotyping
  • Rapid utilize SSO methodology to identify HLA alleles present in a locus-specific PCR-amplified sample. LIFECODES Taq polymerase included in each kit.
  • Results in less than two hours.
  • NO centrifugation or wash steps – reducing overall hands on time.
    Master mix includes primers, dNTP’s and PCR buffer – eliminating extra steps and consumables.

The new MIA FORA NGS FLEX HLA Typing Kit is the only Next Generation Sequencing solution that delivers comprehensive, flexible coverage and an optimized laboratory workflow without compromising performance.

  • Sample to Sequencing in <24 hours
  • Available as 5, 6, 9 and 11 gene kits
  • Upgrade to the power of the MIA FORA 3.0 software
  • Compatible with both Windows Workstations and Linux Servers

Natural killer (NK) cells are lymphocytes of the innate immune system that fight infection by producing cytokines and killing infected cells. Their functional activity is regulated by the interaction between their surface killer cell immunoglobulin-like receptors (KIR) and Class I HLA alleles expressed on the target cell. NK cells will contain more than one type of KIR on their surface and these receptors can be either inhibitory or activating in nature.

There are 14 KIR genes and two pseudogenes located in the leukocyte receptor complex (LRC) on chromosome 19q13.4. Human NK cells express various combinations of these 16 KIR genes with two common haplotypes: Group A, which has more inhibitory receptors and Group B, which has more activating receptors.

Antibody Detection Products

LIFECODES offers the complete antibody product portfolio for the transplant laboratory, with screening, ID and single antigen kits designed to detect and identify HLA antibodies in serum.

The new, enhanced LSA Assays deliver increased coverage, optimized performance, and improve the overall workflow of the LIFECODES® HLA Antibody Analysis portfolio.

LSA-MIC kit is designed to detect antibodies directed against MICA antigens. Publications have suggested that anti-MICA antibodies may play a role in the failure of renal allografts.

Donor Specific Antibodies (DSA) have been shown to be involved in both chronic and acute rejection of transplanted allografts.  Immucor provides solutions for the detection of DSA in transplant samples.  

Other HLA Related Products

For HLA serology, positive - negative controls, complement, HLA Cross - Match, HLA SSP solutions, please contact us.

HLASoft

The Amadeus software covers all the actions and processes used in the operation management of transfusion department: donor records, inviting donors, blood samplings, production of blood, blood storage, plasma delivery to processors, despatch to hospital departments, quarantine plasma, storage of transfusion components and consumables, output for billing healthcare insurance and daily archiving of the whole operation of transfusion department.

The Perseus module for workflow management is a single functional unit which takes up a formalized request at the input from Patology module and at the output submits summary text item which contains the description of the processes which has been made by Laboratory of pathology during the realization of request.

The Perseus module enables both, handsfree operation of the programme and using the touchscreen, which leads to make work easier.

Orpheus is information management software specialized for immunogenetics laboratories and tissue immunogenetics departments, which complies with EFI/ASHI requirements. The system covers a wide range of HLA laboratory activities, including complete laboratory workflow from sample collection to results reporting and billing. Orpheus can be also connected to external systems and devices.

Prometheus is a world-wide used information system for Stem Cells Donor Registries. It covers all key business processes of the registry's daily work, including donor and patient data management, export to BMDW, international donor search process, management of requests, finances, transplant records and donor/patient follow up.

Information and storage management software Cryus is developed specially for Cord Blood Banks, Donor Centers, Stem Cells Collection Centers, Biotech Laboratories and Tissue Banks. The Cryus functions cover complete workflow from collection, processing, production to cryo-storing and transplantation of Hematopoietic Stem Cell products.